Journal of International Oncology ›› 2014, Vol. 41 ›› Issue (5): 364-367.doi: 10.3760/cma.j.issn.1673-422X.2014.05.014

Previous Articles     Next Articles

Progress on serum tumor biomarkers of endometrial carcinoma

Chen Ruifang, Lu Xin   

  1. Department of Female Oncology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai 200011, China
  • Received:2013-12-26 Revised:2014-01-17 Online:2014-05-08 Published:2014-04-28
  • Contact: Lu Xin E-mail:xinludoc@163.com

Abstract: Serum tumor biomarkers are significant for the early diagnosis and treatment, preoperative evaluation, prognosis prediction and relapse surveillance of endometrial carcinoma. Recently, serum CA125 and human epididymal secretory protein 4 are widely recognized  as closely related with staging, metastasis and prognosis of endometrial cancer. In addition, the serum miRNAs are characterized by their features of high stability and specificity.  Omics studies will be helpful for the general assessment of the initiation and progression of endometrial cancer. Insights into these two aspects will facilitate the identifications of new biomarkers with higher sensitivity and specificity for endometrial carcinoma.

Key words: Endometrial neoplasms, Tumor markers, biological, Serum